Spontaneous regression of a congenital melanocytic nevus

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Blaschkolinear congenital melanocytic nevus.

common acquired nevi and an otherwise normal clinical examination. Congenital melanocytic nevi are often classified according to their size [1] . Another attempt of classification in two groups has recently been proposed: type I, the most frequent, with a single lesion involving one anatomic area and type II, less common, with a larger lesion and dozens of smaller ones, with a similar pattern o...

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Spontaneous Involution of Congenital Melanocytic Nevus With Halo Phenomenon

Congenital melanocytic nevus (CMN) is a neural crest-derived hamartoma, which appear at or soon after birth. CMN has a dynamic course and may show variable changes over time, including spontaneous involution. Spontaneous involution of CMN is a rare phenomenon and is often reported in association with halo phenomenon or vitiligo. The mechanism of halo phenomenon is yet to be investigated but is ...

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Giant congenital melanocytic nevus*

Giant congenital melanocytic nevus is usually defined as a melanocytic lesion present at birth that will reach a diameter ≥ 20 cm in adulthood. Its incidence is estimated in <1:20,000 newborns. Despite its rarity, this lesion is important because it may associate with severe complications such as malignant melanoma, affect the central nervous system (neurocutaneous melanosis), and have major ps...

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Congenital Melanocytic Nevus Syndrome: A Case Series.

Congenital melanocytic nevus syndrome (CMNS) is the result of an abnormal proliferation of melanocytes in the skin and central nervous system caused by progenitor-cell mutations during embryonic development. Mutations in the NRAS gene have been detected in many of these cells. We present 5 cases of giant congenital melanocytic nevus, 3 of them associated with CMNS; NRAS gene mutation was studie...

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ژورنال

عنوان ژورنال: Indian Journal of Dermatology, Venereology, and Leprology

سال: 2011

ISSN: 0378-6323

DOI: 10.4103/0378-6323.82418